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Influenza A virus subtype H1N1, also known as A(H1N1), is a subtype of influenza virus A

and the most common cause of influenza (flu) in humans.

 

Some strains of H1N1 are endemic in humans, including the strain(s) responsible for the 1918 flu pandemic

which killed 50–100 million people worldwide.

 

Less virulent H1N1 strains still exist in the wild today, worldwide, causing a small fraction of all influenza-like illness

and a large fraction of all seasonal influenza. H1N1 strains caused roughly half of all flu infections in 2006.

Other strains of H1N1 are endemic in pigs and in birds.

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SWINE FLU H1N1

WHO PANDEMIC ALERT LEVEL

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INFLUENZA A (H1N1) OUTBREAK

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SWINE FLU H1N1 SOS!

WHO PANDEMIC ALERT LEVEL

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SECOND U.S. DEATH LINKED TO SWINE FLU

A Texas woman who had swine flu has died, officials said Tuesday, marking the second death in the United States linked to the virus and the first of a U.S. resident.

The news came as officials in the United States and Mexico, where the outbreak of the H1N1 virus started, were voicing hope that the worst of the new flu strain may be over.

The woman, who died earlier this week, was from Cameron County on the edge of the Gulf of Mexico. The Texas Department of State Health Services said the woman had "chronic underlying health conditions," but did not provide more details.

Dr. Brian Smith, regional director for the department, confirmed the virus was linked to the woman's death and told one CNN affiliate there was "one death confirmed in Cameron County from H1N1 influenza." But speaking with CNN affiliate KRGV-TV, he stopped short of saying it killed her.

"It's certainly part of the clinical picture," Smith said.

The Texas medical examiner's office told CNN the woman had been sick for about a month.

The United States' first death from swine flu came last week: a toddler whose family was visiting Houston, Texas, from Mexico.

By Tuesday afternoon, the number of confirmed cases of the H1N1 virus stood at 1,490 in 22 countries, according to the World Health Organization and the Centers for Disease Control and Prevention. That number includes 822 confirmed cases in Mexico.

WHO has confirmed 30 deaths worldwide from the virus, including 29 in Mexico. The count did not include the most recently reported death in the United States.

There were 403 confirmed cases of the swine flu in the United States, according to the CDC, and another 693 suspected cases counted by various state agencies.

The 403 confirmed U.S. cases are in 38 states, most of them in New York (90), Illinois (82), California (49) and Texas (42), the CDC said Tuesday.

Meanwhile, U.S. officials now recommend that schools stop closing when a case of swine flu is confirmed at a school, Health and Human Services Secretary Kathleen Sebelius said Tuesday.

Scientists believe the H1N1 virus epidemic is no more dangerous than seasonal flu, and schools should act accordingly, Sebelius said.

"This virus does not seem to be as severe as we once thought it would be," she said at the CDC in Atlanta, Georgia.

Sick students should be kept home for seven days, she said, "but the schools should feel comfortable about opening."

Schools that have been closed can reopen, Sebelius said.

Dr. Richard Besser, the CDC's acting director, said that closing schools in a pandemic has a definite benefit. But closing during a general flu outbreak is not required, he said.

"When you get to situations that are approaching general flu, then the downside of closing schools outweighs the benefits," Besser said.

And federal officials have been hearing from local officials "how incredibly difficult and burdensome school closure is," he said.

In Mexico, officials announced plans to reopen government offices and restaurants Wednesday and museums, libraries and churches the following day, citing improvement in the battle against the virus.

U.S. Homeland Security Secretary Janet Napolitano acknowledged claims by Mexican authorities who believe that their cases have peaked.

"I have no reason to think that is inaccurate," Napolitano said.

"What the epidemiologists are seeing now with this particular strain of H1N1 is that the severity of the disease, the severity of the flu -- how sick you get -- is not stronger than regular seasonal flu."

Health officials have begun using the virus's clinical name, H1N1, to reflect that it's a combination of several different types of flu and to reduce confusion about whether eating pork can spread the virus, which it cannot.

Officials from WHO and the CDC plan to monitor developments in the Southern Hemisphere, where flu season arrives over the next few months as winter begins there.

Those results will help determine whether a stronger strain of the virus will return to the United States and the Northern Hemisphere during the fall flu season.

In Mexico City, about 35,000 public venues were shut down, transforming the bustling metropolis of 20 million people into a ghost town overnight.

Soccer games were postponed, restaurants served only takeout orders, and Sunday Mass -- which usually draws millions of worshippers -- was canceled.

"It's surreal to say the least. And the masks add to that," said Cristiano Oliveira, a Brazilian living in Mexico City for the past year and a half. "There was, to me, at least the impression that Mexico City would never slow down. And now it's halted."

In the city's Condesa neighborhood, Alfredo Sono Dillman whiled away the days watching movies on a home computer.

"We all live inside our houses, because the schools have been canceled until May 11," the 15-year-old said. "I'm not scared like last week. This week has been easier. Now we know much better what is going on."

Early Tuesday, the Mexican and Chinese government sent chartered flights to each other's countries to pick up their respective nationals stranded or quarantined because of the global swine flu outbreak.

An Aeromexico flight made several stops Tuesday throughout China to collect nearly 70 Mexican citizens who were being held in quarantine across the communist nation as part of its strict swine flu-control measures.

At least two Mexicans remained in quarantine in Beijing. Meanwhile, a U.S. Embassy official said four Americans are or were quarantined in China: two in Beijing and two in southern Guangdong province.

China suspended all flights into and out of Mexico after a 25-year-old Mexican man who arrived Thursday in Shanghai from Mexico City became the Asian country's first confirmed case of the virus.

As a result, 200 Chinese citizens were stranded in Mexico City and Tijuana. A China Southern Airlines flight was expected to fetch them Tuesday, state media said.

Also Tuesday, the U.S. Navy said it has canceled the deployment of one of its ships because of a number of possible cases of swine flu.

The USS Dubuque, an amphibious transport dock ship, was due to deploy June 1 to the South Pacific on a humanitarian mission, according to Cmdr. Joseph Surette, a Navy spokesman.

He said there was one confirmed case of H1N1 virus and 49 possible other cases among crew members over the past several days. The 50 crew members are off the ship recovering and being given Tamiflu medication, Surette said.

The ship is being scrubbed and disinfected, and the remaining 370 crew members are being given Tamiflu as a precaution, according to Surette.

WHO officials said there were no immediate plans to raise its pandemic alert to the highest level, 6.

 

WHO RENAMES “SWINE FLU” TO “INLUENZA A (H1N1)”

Influenza A (H1N1) contains avian, human and swine influenza strains

The situation continues to evolve rapidly. As of 18:00 GMT+1, 2 May 2009, 16 countries have officially reported 658 cases of influenza A (H1N1) infection.

Mexico has reported 397 confirmed human cases of infection, including 16 deaths. The higher number of cases from Mexico in the past 48 hours reflects ongoing testing of previously collected specimens. The United States Government has reported 160 laboratory confirmed human cases, including one death.

The following countries have reported laboratory confirmed cases with no deaths - Austria (1), Canada (51), China, Hong Kong Special Administrative Region (1), Costa Rica (1), Denmark (1), France (2), Germany (6), Israel (3), Netherlands (1), New Zealand (4), Republic of Korea (1), Spain (13), Switzerland (1) and the United Kingdom (15).

Further information on the situation will be available on the WHO website on a regular basis.

WHO advises no restriction of regular travel or closure of borders. It is considered prudent for people who are ill to delay international travel and for people developing symptoms following international travel to seek medical attention, in line with guidance from national authorities.

There is also no risk of infection from this virus from consumption of well-cooked pork and pork products. Individuals are advised to wash hands thoroughly with soap and water on a regular basis and should seek medical attention if they develop any symptoms of influenza-like illness.

 

The UN's World Health Organization has raised the alert over swine flu to level five - one short
of a full-blown global epidemic, or pandemic.

 

A phase five alert means human-to-human transmission in at least two countries.

The move comes after a 23-month-old Mexican child died in Texas - the first death from swine flu outside Mexico, where the outbreak originated.

In Spain, officials confirmed the first case of swine flu in a person who had not travelled to Mexico.

Mexico's President Felipe Calderon addressed the nation late on Wednesday, announcing the partial suspension of non-essential work and services from 1 May to 5 May.

The efforts of the government were concentrated on containing the virus, Mr Calderon said, urging people to stay at home with their families during the shutdown.

He said he was "proud" of the response of Mexicans to the crisis, and assured people Mexico was well-stocked with anti-viral medicines.

Announcing the latest alert level after an emergency WHO meeting in Geneva, Director General Margaret Chan urged all countries to activate their pandemic plans, including heightened surveillance and infection-control measures.

She said action should be undertaken with "increased urgency". She added: "It really is the whole of humanity that is under threat in a pandemic."

But she also said the world was "better prepared for an influenza pandemic than at any time in history". Ms Chan said that for the first time, the pandemic could be tracked in real time.

This was necessary, she added, because the virus could mutate at any time into a more dangerous strain - or a milder one.

Border controls?

The Mexican boy who died in the US fell ill during a visit to relatives in southern Texas earlier this month. He was transferred to a hospital in Houston, where he died on Monday night.

Speaking in Washington, President Barack Obama offered his condolences and said the federal government was doing the utmost to contain the virus.

He also urged local public-health bodies to be vigilant and said schools with confirmed cases "should consider closing".

Officials put the number of suspected deaths from swine flu in Mexico at 159, although just seven deaths have been confirmed, with 26 infections positively tested.

Texas Governor Rick Perry said closing the US border with Mexico was an option, but added that taking that step now would be "a little premature".

Giving a televised news conference on Wednesday evening, US President Barack Obama said health officials were not recommending closing the border.

"The key now is to just make sure we are maintaining great vigilance, that everybody responds appropriately when cases do come up," Mr. Obama said.

Since the virus emerged last week, it has also spread to Canada, Europe, Israel, and New Zealand.

Peru became the latest country to confirm it was treating a patient suffering from swine flu. An Argentine woman who had recently travelled to Mexico was Peru's first case of the virus, the country's health minister said late on Wednesday.

Several countries have restricted travel to Mexico and many tour operators have cancelled holidays.

France will ask the European Union on Thursday to suspend all flights going to Mexico because of the flu outbreak, Health Minister Roselyne Bachelot said.

The WHO, however, says measures like travel bans are unlikely to prove effective.

'Social distancing'

In Spain, the government said the first person to contract swine flu without having travelled to Mexico was the boyfriend of a young woman who had recently returned from there.

Spanish Health Minister Trinidad Jimenez said such cases were to be expected.

In total, the number of confirmed cases in Spain rose from two to 10 on Wednesday. None of the patients is seriously ill.

In Mexico, the search for the source of the outbreak continues, with the focus on the vicinity of a pig farm in the eastern part of the country.

The Mexican government is urging against jumping to conclusions and is suggesting the possibility remains that the virus originated outside the country.

Schools across Mexico have closed, public gatherings are restricted and archaeological sites have been placed off-limits.

Mexico City's chamber of commerce estimated restrictions in the city were costing businesses there at least 777 million pesos ($57m, £39m) per day.

WHO official Keiji Fukuda said other countries also needed to consider "social distancing" measures such as closing schools and delaying public meetings.

Meanwhile, Ghana has become the latest country to ban pork imports as a precaution against swine flu, though no cases have been found in the West African country.

Ms Chan, the WHO director, stressed on Wednesday that there was no danger from eating properly-cooked pork. She advised hygiene measures such as hand-washing to prevent infection and said it was important "to maintain a level of calm". /.

 

 

 

 

 

 

 

 

 

 

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